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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC1 All Species: 15.45
Human Site: T1628 Identified Species: 30.91
UniProt: Q9H1A4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1A4 NP_073153.1 1944 216500 T1628 P V D V D T N T P C Y A L L E
Chimpanzee Pan troglodytes XP_515601 1394 155989 L1112 T L L P E L H L L K Q I K V K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532958 1943 216470 M1627 P V D V D T N M P C Y A L L E
Cat Felis silvestris
Mouse Mus musculus P53995 1944 216068 T1628 P V D V D T N T P C Y A L I E
Rat Rattus norvegicus NP_001101241 1944 216060 T1628 P V D V D T N T P C Y A L I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419303 1945 216100 T1630 P V D V D S N T P C Y A L I E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921168 1979 220132 K1673 P V D V D S L K P C Y A L L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573025 2030 227256 K1706 P R D I D T N K L C L A N I S
Honey Bee Apis mellifera XP_001122449 1939 218025 Q1616 P K D I D S N Q Y C Y A I V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202400 910 100394 S628 C I I G E L R S L K S V R I L
Poplar Tree Populus trichocarpa XP_002312165 1929 212815 L1642 A F S S D P S L I A F A Q L C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196175 1678 186257 S1396 T L Y P R L P S G P N D N R C
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 N.A. 97.3 N.A. 92.1 92.9 N.A. N.A. 81.7 N.A. 66 N.A. 33.6 38 N.A. 25.2
Protein Similarity: 100 71.5 N.A. 98.5 N.A. 96 96.5 N.A. N.A. 90.2 N.A. 79 N.A. 52.2 59.1 N.A. 33.8
P-Site Identity: 100 0 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 73.3 N.A. 46.6 46.6 N.A. 0
P-Site Similarity: 100 33.3 N.A. 93.3 N.A. 100 100 N.A. N.A. 100 N.A. 86.6 N.A. 60 80 N.A. 26.6
Percent
Protein Identity: 28.5 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 47 N.A. N.A. 45.8 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 9 0 75 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 67 0 0 0 0 17 % C
% Asp: 0 0 67 0 75 0 0 0 0 0 0 9 0 0 9 % D
% Glu: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 42 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 17 0 0 0 0 9 0 0 9 9 42 0 % I
% Lys: 0 9 0 0 0 0 0 17 0 17 0 0 9 0 9 % K
% Leu: 0 17 9 0 0 25 9 17 25 0 9 0 50 34 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 59 0 0 0 9 0 17 0 0 % N
% Pro: 67 0 0 17 0 9 9 0 50 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 9 0 9 0 9 % Q
% Arg: 0 9 0 0 9 0 9 0 0 0 0 0 9 9 0 % R
% Ser: 0 0 9 9 0 25 9 17 0 0 9 0 0 0 9 % S
% Thr: 17 0 0 0 0 42 0 34 0 0 0 0 0 0 0 % T
% Val: 0 50 0 50 0 0 0 0 0 0 0 9 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 9 0 59 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _